Humanized mouse and rat models are used as an instrument in laboratories for modeling human biology and disease. This model is also known as Knocking Model, in which a mouse gene is replaced by either a human gene or a genomic sequence. Technological advances over the last few years have initiated the Genetic Engineering of Mouse Genome (GEM). This modification includes the deletion of a gene from mouse genome and replacing it by human ortholog or gene, which is termed as knockin. Moreover, discovery of new methods for treating liver and bone marrow have alsoenabled replacing ofhumanized liver and bone marrow with the liver and bone marrow of a mouse. In recent days, scientists prefer using of a mouse model, as the process of death to birth is very rapid for this kind of species. Increasing research and development activity in pharmaceutical sectormakes this market more demanding in the near future.
The global humanized mouse &rat model market is propelled by the rise in .Some other factors which drives the global market of humanized mouse and rat model is growing development of contract research organization coupled with thegrowth of pharmaceutical industries across the globe. Rising prevalence of cancer and usage of personalized medicines is one of the significant factor which is anticipated to augment the growth of this market. Further down, the surge in production of monoclonal antibodiesand stem cell exploration, is considered to be aprime factor driving the growth of the market. In addition to this, rise in range of applicationsis further estimated to make the global humanized and rat model market more demanding in the foreseeable future.numberof applications which includes oncology, infection diseases, and toxicology among others.
The global humanized mouse &rat model market in the report is segmented by .Based on application, the market has been analyzed ashematopoiesis, oncology, toxicology, autoimmunity, infection diseases, and others.Moving forward, the humanized mouse &rat model market has been bifurcatedas end-user which includes contract research organization, pharmaceutical industry, and others.Geographically the market is segmentedinto North America, Europe, Asia-Pacific, Middle East and Africa and Latin America.modelstype which includescell-based models and genetic models. The cell-based models type is further sub-segmented as BLT model, CD34 model, and PBMC model.
Technology and well-structured contract research organizations in Asia-Pacific, makes the region hold the largest market share. Moreover, accessibility of research .Rising focuson oncology research in the U.S., Germany, Italy and France, has therefore increased the demand ofhumanized mouse &rat model market in these regions. Moving forward, rapid growth of personalized medicines and development of biomedicalindustries in countries like Brazil and Chile, therefore, creates a high demand for humanized mouse &rat model in the Latin-American region. Furtherdown,in Middle-East and Africa region, increasing investment in pharmaceutical industries and in animal research, fuel the growth of the humanized mouse &rat model market. Additionally, increase in demand for humanized mouse &rat models for various application areas such ashematopoiesis,oncology, toxicology, infection diseases, and others are expectedto lead the market growth of the globalhumanized mouse &rat modelduring the estimated period.centrescoupled with the growing biotechnology industries are the maindriving forces behind the Europe and North America market.
However, high cost of models and regulatory issue for moral use of animals may impose a restriction on the growth of the global humanized mouse &rat model market.
Some of the major players in the global humanized mouse &rat model includeAxenis S.A.S., Crown Bioscience, Inc., Champions Oncology, Charles River Laboratories, GenOway S.A., Harbour Antibodies BV, Ingenious Targeting Laboratory, and Taconic Biotechnology Co.
Global Humanized Mouse & Rat Model Market: By Models Type
Global Humanized Mouse & Rat Model Market: By Application
Global Humanized Mouse & Rat Model Market: By End-User
Global Humanized Mouse & Rat Model Market: By Geography